Sequence specific detection of DNA using nicking endonuclease signal amplification (NESA)
نویسندگان
چکیده
منابع مشابه
Sequence specific detection of DNA using nicking endonuclease signal amplification (NESA)
We have developed a new method for identifying specific single- or double-stranded DNA sequences called nicking endonuclease signal amplification (NESA). A probe and target DNA anneal to create a restriction site that is recognized by a strand-specific endonuclease that cleaves the probe into two pieces leaving the target DNA intact. The target DNA can then act as a template for fresh probe and...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2007
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkm654